منابع مشابه
Go Directly (or Indirectly) to Gq
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Cholinomimetic drugs can elicit some or all of the effects that acetylcholine (ACh) produces. This class of drugs includes agents that act directly as agonists at cholinoreceptors and agents that act indirectly by inhibiting the enzymatic destruction of endogenous ACh (i.e., cholinesterase inhibitors).The directly acting cholinomimetics can be subdivided into agents that exert their effects pri...
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While epidemiological studies have suggested that aluminum is a risk factor for Alzheimer disease (AD), the underlying mechanism through which aluminum leads to AD remains unknown. Despite the lack of evidence linking aluminum to AD that have motivated many to avoid using materials such as cooking utensils made with the metal, researchers have yet to investigate the precise effects of aluminum ...
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The introduction of one acetyl group into the chymotrypsin molecule by reaction with p-nitrophenyl acetate gives rise to an enzymatically inactive monoacetylated protein that rapidly loses its acetyl group and becomes active again in solutions of dilute alkali or primary alcohols." 2 On the other hand, the well-known polyacetylation of proteins with acetic anhydride, as described by Fraenkel-Co...
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ژورنال
عنوان ژورنال: Neuron
سال: 1999
ISSN: 0896-6273
DOI: 10.1016/s0896-6273(00)80840-5